Workshop on Radiopharmaceutical Therapy (RPT) Normal Tissue Effects in the Clinic (TEC)
RPT-TEC-2022

September 24 - 29, 2022

CSI

Commitees Speakers Topics Programme Participants Location Fee

Co-organized and Supported by:
Organizing Committee:

W. Bolch, J. Capala, M. Cremonesi, Y. Dewaraja, J. Gear, G. Glatting, R.F. Hobbs, A. Kesner, A.P. Kiess, J. O’Donoghue, D. Pryma, N. Pandit-Taskar, G. Sgouros, L. Strigari, S. Tagawa, T. Yusufaly, C. Uribe

List of Speakers:
P. Bernhardt (Gothenburg U)
L. Bodei (Memorial Sloan Kettering Cancer Center)
Y. Dewaraja (U MichigaN)
J. Gear (Inst Cancer Research: Royal Cancer Hospital)
R. Hobbs (Johns Hopkins U)
V. Jardine (Bayer AG) *
A. Kiess (Johns Hopkins U)
M. Morris (Memorial Sloan Kettering Cancer Center) *
J. O'Donoghue (Memorial Sloan Kettering Cancer Center)
N. Pandit-Taskar (Memorial Sloan Kettering Cancer Center)
G. Sgouros (Johns Hopkins U)
I. Tworowska (RADIOMEDIX, Inc)
C. Uribe (BC Cancer & U. British Columbia)

(*): to be confirmed.

About:

We are organizing a 4-day international workshop to review the collective clinical experience in radiopharmaceutical therapy (RPT) as it relates to the relationship between toxicity and tissue absorbed dose.

The objectives of the workshop are to arrive at normal organ toxicity avoidance (NOTA) absorbed doses, expressed as two-Gy equieffective dose (EQD2) applicable to different RPT agent/radionuclide combinations. We envision a gathering whereby physicians with experience treating patients with RPT will compile/describe their patient toxicity experience for different agents and administered activity (AA) schedules. These data will be used by the physics attendees to reconstruct organ absorbed dose estimates. We anticipate an iterative process whereby the physicists ask the physicians for their best estimates of potential input (e.g., clearance kinetics, localization, potential impact of prior treatment on observed tissue toxicity); some of this data may also be available from pre and post-imaging (i.e., theranostics) RPT imaging and also from the literature.

The product of this workshop will be a single or series of QUANTEC-like publications for RPT agents (RPT-TEC). We also anticipate that a metaanalysis of clinical experience in RPT will arise from the workshop. Recognizing that input into deriving NOTA absorbed doses will be a combination of rigorous published data and physician’s experience from ongoing (unpublished) patient therapy experience, we will implement the NCCN categorization to rank the reliability of the evidence supporting recommended NOTA absorbed dose estimates.

Programme:
Meeting Location:

Mon-Repos, Corfu, Greece
(click here for a larger map, for a menu click on the top left icon of the map, GPS: geo:39.606101,19.926115)


Accommodations:

Guaranteed hotel availability is for a very limited time! Please make your hotel reservations ASAP!

Registration Fee:

Please register using the registration page, which is common for all Corfu events. The registration fee is 250€. For young researchers (students and 1st year postdocs) it is 150€. For remote participants the fee is 65€. Payments may be transferred to the NTUA bank account shown in this form and the receipt emailed to Mrs Ifigeneia Moraiti.