Figure 1. Intense thermal damage of silicone IOL ablation craters  after Er:YAG laser radiation. 

Figure 2.  A proposed pattern for formation of sliding levels with the use of laser ablation.

Figure 3. (a) SEM image of the ablation crater in a PMMA intraocular lens (ARTISAN Aphakic, 18.00 D). Laser parameters: Nd:YAG laser (4th harmonic, λ=266 nm), energy fluence F= 4.07 J/cm². (b) Details of the laser ablated crater walls, corresponding to the area indicated by o in (a).

Figure 6.   (left) Water content h vs relative humidity RH for samples indicated on the plot at room temperature, experimental data (points) fitting to GAB equation (lines)  (right) Temperature of maximum depolarization current, Τ_α, vs relative humidity.

From: L. Hartmann, A. Spanoudaki, A. Kyritsis, P. Pissis, R. Pelster, N. Shinyashiki, J. C. Rodriguez Hernandez, J. L. Gomez Ribelles, M. Monleon Pradas, Dielectric studies of molecular dynamics and hydration properties of poly(hydroxy ethyl acrylate)-co-poly(ethyl acrylate) copolymers, Proc. ISEMA 2009, 8th International Conference on Electromagnetic Wave Interaction with Water and Moist Substances, June 2009, Helsinki (Finnland), 8 pages.

Figure 7. Frequency dependence of dielectric losses in 90/10 PHEA-co-PEA hydrogels at two temperatures indicated on the plot and several water contents (relative humidity, RH).

From: P. Pissis, A. Kyritsis, G. Gallego Ferrer, M. Monléon Pradas, and J. L. Gómez Ribelles, “Water in Hydrogels Studied by Dielectric, Thermal and Water Sorption/Diffusion Techniques”, Subsurface Sensing Technologies and Applications Vol. 1, No. 4, 2000.

THALES proposal: “Experimental and theoretical study of biophysical properties and morphology of polymeric intraocular lenses and ophthalmic tissues during laser irradiation for vision improvement - BiophysIOL”.

· In this project, the study of basic biophysical parameters of laser interaction with surfaces of polymeric material (intraocular lenses, IOLs) and ex vivo corneas is proposed. The main aim is to examine the factors which affect the results of modern refractive surgery, as well as to extend the laser procedures for correction of presbyopia and other abnormalities.

· The researchers that form the scientific team of this project were involved in the study of partial problems before and they have obtained very interesting experimental evidence for the “Project Concept and Objectives” of this proposal.

· Some interesting preliminary results are presented here.

School of Applied Mathematical and Physical Sciences,

Physics Department

NATIONAL TECHNICAL UNIVERSITY OF ATHENS

Experimental and theoretical data related to BiophysIOL project

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Greek Version